Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
soluble | - |
Homo sapiens | - |
- |
soluble | - |
Rattus norvegicus | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
24000 | - |
COMT I, gel filtration, sedimentation data | Rattus norvegicus |
47500 | - |
COMT II, gel filtration, sedimentation data | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | physiological role is the inactivation of catecholamine hormones and neurotransmitters as well as detoxification of a variety of xenobiotic amines and drugs | ? | - |
? | |
additional information | Rattus norvegicus | physiological role is the inactivation of catecholamine hormones and neurotransmitters as well as detoxification of a variety of xenobiotic amines and drugs | ? | - |
? | |
additional information | Oryctolagus cuniculus | physiological role is the inactivation of catecholamine hormones and neurotransmitters as well as detoxification of a variety of xenobiotic amines and drugs | ? | - |
? | |
S-adenosyl-L-methionine + a catechol | Homo sapiens | - |
? | - |
? | |
S-adenosyl-L-methionine + a catechol | Rattus norvegicus | - |
? | - |
? | |
S-adenosyl-L-methionine + a catechol | Oryctolagus cuniculus | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
2 forms | - |
Oryctolagus cuniculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
brain | - |
Rattus norvegicus | - |
heart | - |
Rattus norvegicus | - |
kidney | - |
Rattus norvegicus | - |
liver | - |
Homo sapiens | - |
liver | - |
Rattus norvegicus | - |
liver | - |
Oryctolagus cuniculus | - |
lung | - |
Homo sapiens | - |
lung | - |
Rattus norvegicus | - |
lung | - |
Oryctolagus cuniculus | - |
placenta | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Homo sapiens |
additional information | - |
- |
Rattus norvegicus |
Storage Stability | Organism |
---|---|
-20°C, or -60°C, 50 mM Tris-HCl, pH 7.5, 20 mM 2-mercaptoethanol, 20% v/v glycerol, 60-80% of activity retained after 6 months | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | physiological role is the inactivation of catecholamine hormones and neurotransmitters as well as detoxification of a variety of xenobiotic amines and drugs | Homo sapiens | ? | - |
? | |
additional information | physiological role is the inactivation of catecholamine hormones and neurotransmitters as well as detoxification of a variety of xenobiotic amines and drugs | Rattus norvegicus | ? | - |
? | |
additional information | physiological role is the inactivation of catecholamine hormones and neurotransmitters as well as detoxification of a variety of xenobiotic amines and drugs | Oryctolagus cuniculus | ? | - |
? | |
S-adenosyl-L-methionine + a catechol | - |
Homo sapiens | ? | - |
? | |
S-adenosyl-L-methionine + a catechol | - |
Rattus norvegicus | ? | - |
? | |
S-adenosyl-L-methionine + a catechol | - |
Oryctolagus cuniculus | ? | - |
? |