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Literature summary for 2.1.1.6 extracted from

  • Williams-Gray, C.H.; Hampshire, A.; Robbins, T.W.; Owen, A.M.; Barker, R.A.
    Catechol O-methyltransferase Val158Met genotype influences frontoparietal activity during planning in patients with Parkinsons disease (2007), J. Neurosci., 27, 4832-4838.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine COMT genotype directly influences cognitive phenotype in Parkinson’s disease through altering activation in a frontoparietal executive neural network. COMT genotype has differing effects on prefrontal function according to underlying dopaminergic state Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Synonyms

Synonyms Comment Organism
COMT
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Homo sapiens