Literature summary for 2.1.1.61 extracted from

Yan, Q.; Bykhovskaya, Y.; Li, R.; Mengesha, E.; Shohat, M.; Estivill, X.; Fischel-Ghodsian, N.; Guan, M.X.
Human TRMU encoding the mitochondrial 5-methylaminomethyl-2-thiouridylate-methyltransferase is a putative nuclear modifier gene for the phenotypic expression of the deafness-associated 12S rRNA mutations (2006), Biochem. Biophys. Res. Commun., 342, 1130-1136.

Search for more literature for 2.1.1.61

Application

Application	Comment	Organism
additional information	putative nuclear modifier gene TRMU may modulate the phenotypic manifestation of the deafness-associated mitochondrial 12S rRNA mutations	Homo sapiens

Cloned(Commentary)

Cloned (Comment)	Organism
TRMU-GFP fusion protein transfected into 143B cell line	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	localizes exclusively to mitochondria, even when overexpressed	Homo sapiens	5739	-

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
47750	-	sequence analysis	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	O75648	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	moderately expressed	Homo sapiens	-
colon	low level	Homo sapiens	-
heart	abundantly expressed in tissues with high metabolic rates	Homo sapiens	-
kidney	abundantly expressed in tissues with high metabolic rates	Homo sapiens	-
leukocyte	low level	Homo sapiens	-
liver	low level	Homo sapiens	-
lung	low level	Homo sapiens	-
placenta	moderately expressed	Homo sapiens	-
skeletal muscle	abundantly expressed in tissues with high metabolic rates	Homo sapiens	-
small intestine	moderately expressed	Homo sapiens	-
spleen	moderately expressed	Homo sapiens	-
thymus	low level	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
5-methylaminomethyl-2-thiouridylate-methyltransferase	-	Homo sapiens
TRMU	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)