Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A-549 cell | - |
Homo sapiens | - |
NCI-H1299 cell | - |
Homo sapiens | - |
NCI-H1355 cell | - |
Homo sapiens | - |
NCI-H23 cell | - |
Homo sapiens | - |
NCI-H441 cell | - |
Homo sapiens | - |
NCI-H460 cell | - |
Homo sapiens | - |
NHBE cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA containing 6-O-methylguanine + [protein]-L-cysteine | - |
Homo sapiens | DNA lacking 6-O-methylguanine + [protein]-S-methyl-L-cysteine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MGMT | - |
Homo sapiens |
O6-methylguanine-DNA-methyltransferase | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | promoter methylation of O6-methylguanine-DNA-methyltransferase in lung cancer is regulated by p53 | additional information |
General Information | Comment | Organism |
---|---|---|
physiological function | MGMT promoter methylation modulated by p53 status can partially promote p53 mutation occurrence in advanced lung tumors | Homo sapiens |