Application | Comment | Organism |
---|---|---|
medicine | first case of azathioprine-associated AML linked to low thiopurine S-methyltransferase enzyme activity | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
TPMT*3B | polymorphism, single nucleotide substitution G460A | Homo sapiens |
TPMT*3C | polymorphism, single nucleotide substitution A719G | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + a thiopurine | Homo sapiens | - |
S-adenosyl-L-homocysteine + a thiopurine S-methylether | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + a thiopurine | - |
Homo sapiens | S-adenosyl-L-homocysteine + a thiopurine S-methylether | - |
? |
Synonyms | Comment | Organism |
---|---|---|
thiopurine S-methyltransferase | - |
Homo sapiens |
TPMT | - |
Homo sapiens |