Application | Comment | Organism |
---|---|---|
medicine | mercaptopurine dose can be adjusted on the basis of TPMT genotype to mitigate toxicity in pediatric patients with acute lymphoblastic leukemia | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + mercaptopurine | - |
Homo sapiens | S-adenosyl-L-homocysteine + methylmercaptopurine | - |
? | |
S-adenosyl-L-methionine + thioinosine monophosphate | - |
Homo sapiens | S-adenosyl-L-homocysteine + methylthioinosine monophosphate | - |
? | |
S-adenosyl-L-methionine + thioinosine triphosphate | - |
Homo sapiens | S-adenosyl-L-homocysteine + methylthioinosine triphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
thiopurine-S-methyl-transferase | - |
Homo sapiens |
TPMT | - |
Homo sapiens |