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Literature summary for 2.1.1.67 extracted from
- Capillary electrophoresis determination of thiopurine methyl transferase activity in erythrocytes (2009), J. Chromatogr. B, 877, 1943-1945.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| erythrocyte | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + 6-mercaptopurine | - |
Homo sapiens | S-adenosyl-L-homocysteine + 6-methylmercaptopurine | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| thiopurine methyl transferase | - |
Homo sapiens |
| TPMT | - |
Homo sapiens |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Homo sapiens | decreased activity of TPMT is associated with hematopoietic toxicity after administration of standard doses of 6- mercaptopurine or azathioprine | down |
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Release 2023.1 (January 2023)
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