Literature summary for 2.1.1.72 extracted from

Bonnist, E.Y.; Liebert, K.; Dryden, D.T.; Jeltsch, A.; Jones, A.C.
Using the fluorescence decay of 2-aminopurine to investigate conformational change in the recognition sequence of the EcoRV DNA-(adenine-N6)-methyltransferase on enzyme binding (2012), Biophys. Chem., 160, 28-34.

Search for more literature for 2.1.1.72

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.0003	-	DNA adenine	in 50 mM NaCl, 50 mM HEPES, 1 mM EDTA, pH 7.5, temperature not specified in the publication	Escherichia coli
0.012	-	S-adenosyl-L-methionine	in 50 mM NaCl, 50 mM HEPES, 1 mM EDTA, pH 7.5, temperature not specified in the publication	Escherichia coli

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Escherichia coli

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + DNA adenine	the EcoRV DNA methyltransferase methylates the first adenine in the GATATC recognition sequence	Escherichia coli	S-adenosyl-L-homocysteine + DNA 6-methyladenine	-	?

Synonyms

Synonyms	Comment	Organism
DNA-(adenine-N6)-methyltransferase	-	Escherichia coli
EcoRV	-	Escherichia coli

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)