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Literature summary for 2.1.1.77 extracted from

  • Chen, T.; Nayak, N.; Majee, S.M.; Lowenson, J.; Schaefermeyer, K.R.; Eliopoulos, A.C.; Lloyd, T.D.; Dinkins, R.; Perry, S.E.; Forsthoefel, N.R.; Clarke, S.G.; Vernon, D.M.; Zhou, Z.S.; Rejtar, T.; Downie, A.B.
    Substrates of the Arabidopsis thaliana protein isoaspartyl methyltransferase 1 identified using phage display and biopanning (2010), J. Biol. Chem., 285, 37281-37292.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.77

Activating Compound

Activating Compound Comment Organism Structure
Urea recombinant enzyme relative activity is greatest in liquid assays in 1 M urea Arabidopsis thaliana

Inhibitors

Inhibitors Comment Organism Structure
S-adenosyl-L-homocysteine potent inhibitor Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + protein D-isoaspartate Arabidopsis thaliana
-
 S-adenosyl-L-homocysteine + protein D-isoaspartate alpha-methyl ester
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-

Purification (Commentary)

Purification (Comment) Organism
nickel column chromatography Arabidopsis thaliana

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + 60 S ribosomal protein L27
-
 Arabidopsis thaliana S-adenosyl-L-homocysteine +
-
 ?
S-adenosyl-L-methionine + ATHSP17.4 protein
-
 Arabidopsis thaliana S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + bovine serum albumin
-
 Arabidopsis thaliana S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + carboxyesterase 12
-
 Arabidopsis thaliana S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + cinnamoyl-CoA reductase family protein
-
 Arabidopsis thaliana S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + early flowering 8 protein
-
 Arabidopsis thaliana S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + mitochondrial glycoprotein family protein/MAM33
-
 Arabidopsis thaliana S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + oligocellula 2 protein
-
 Arabidopsis thaliana S-adenosyl-L-homocysteine +
-
 ?
S-adenosyl-L-methionine + ovalbumin
-
 Arabidopsis thaliana S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + PIRL8 protein
-
 Arabidopsis thaliana S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + PRH75 protein
-
 Arabidopsis thaliana S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + protein D-isoaspartate
-
 Arabidopsis thaliana S-adenosyl-L-homocysteine + protein D-isoaspartate alpha-methyl ester
-
 ?
S-adenosyl-L-methionine + UDP-xylose synthase 5
-
 Arabidopsis thaliana S-adenosyl-L-homocysteine + ?
-
 ?

Synonyms

Synonyms Comment Organism
PIMT1
-
 Arabidopsis thaliana
protein isoaspartyl methyltransferase 1
-
 Arabidopsis thaliana