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Literature summary for 2.1.1.8 extracted from
- Guinea pig brain histamine N-methyltransferase: purification and partial characterization (1983), J. Neurochem., 41, 113-118.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| S-adenosylhomocysteine | - |
Cavia porcellus |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Cavia porcellus | |
| 0.006 | - |
S-adenosyl-L-methionine | - |
Cavia porcellus | |
| 0.014 | - |
histamine | - |
Cavia porcellus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 29000 | - |
gel filtration, SDS-PAGE | Cavia porcellus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cavia porcellus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Cavia porcellus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Cavia porcellus | - |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -80°C, 3 months | Cavia porcellus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + histamine | - |
Cavia porcellus | S-adenosyl-L-homocysteine + Ntau-methylhistamine | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 29000, SDS-PAGE | Cavia porcellus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
2 optima at pH 7.5 and pH 9.0, brain enzyme | Cavia porcellus |
| 9 | - |
2 optima: pH 7.5 and pH 9.0, brain enzyme | Cavia porcellus |
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Release 2023.1 (January 2023)
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