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Literature summary for 2.1.1.86 extracted from

  • Lienard, T.; Gottschalk, G.
    Cloning, sequencing and expression of the genes encoding the sodium translocating N5-methyltetrahydromethanopterin: coenzyme M methyltransferase of the methylotrophic archaeon Methanosarcina mazei Gö1 (1998), FEBS Lett., 425, 204-208.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
all of these subunits are shown to be heterologously expressed in minicells of the Escherichia coli mutant DK6. Sequence comparisons with the methyltransferases of thermophilic and hypothermophilic methanogenic archaea Methanosarcina mazei

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane membrane-associated enzyme Methanosarcina mazei 16020
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Organism

Organism UniProt Comment Textmining
Methanosarcina mazei O59640 and P80655 and O59638 and P80653 and P80651 and P80654 and P80656 and P80650 O59640: subunit A, P80655: subunit B, O59638: subunit C, P80653: subunit D, P80651: subunit E, P80654: subunit F, P80656: subunit G, P80650: subunit H
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Methanosarcina mazei DSM 3647 O59640 and P80655 and O59638 and P80653 and P80651 and P80654 and P80656 and P80650 O59640: subunit A, P80655: subunit B, O59638: subunit C, P80653: subunit D, P80651: subunit E, P80654: subunit F, P80656: subunit G, P80650: subunit H
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-methyl-5,6,7,8-tetrahydromethanopterin + 2-mercaptoethanesulfonate the enzyme uses a transmethylation reaction to drive an energy-conserving sodium ion pump Methanosarcina mazei 5,6,7,8-tetrahydromethanopterin + 2-(methylthio)ethanesulfonate
-
?
5-methyl-5,6,7,8-tetrahydromethanopterin + 2-mercaptoethanesulfonate the enzyme uses a transmethylation reaction to drive an energy-conserving sodium ion pump Methanosarcina mazei DSM 3647 5,6,7,8-tetrahydromethanopterin + 2-(methylthio)ethanesulfonate
-
?

Synonyms

Synonyms Comment Organism
N5-methyltetrahydromethanopterin:coenzyme M methyltransferase
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Methanosarcina mazei