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Literature summary for 2.1.3.3 extracted from

  • Koger, J.B.; Howell, R.G.; Kelly, M.; Jones, E.E.
    Purification and properties of porcine liver ornithine transcarbamylase (1994), Arch. Biochem. Biophys., 309, 293-299.
    View publication on PubMed
Search for more literature for 2.1.3.3

Inhibitors

Inhibitors Comment Organism Structure
Delta-N-Phosphonoacetyl-L-ornithine
-
 Sus scrofa
Phenylglyoxal complete inactivation after 1 h incubation Sus scrofa
phosphate
-
 Sus scrofa

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
37000
-
 3 * 37000, SDS-PAGE Sus scrofa
107000
-
 gel filtration, sedimentation equilibrium Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
ammonium sulfate, Sephacryl S-200, delta-N-phosphonoacetyl-L-ornithine affinity chromatography Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
26.4
-
-
 Sus scrofa

Storage Stability

Storage Stability Organism
-20°C, several weeks, no loss of activity Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
carbamoyl phosphate + L-ornithine
-
 Sus scrofa phosphate + L-citrulline
-
 ?

Subunits

Subunits Comment Organism
trimer 3 * 37000, SDS-PAGE Sus scrofa

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
 sharp decrease in activity between pH 8.4 and 8.8 Sus scrofa

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.00013
-
 Delta-N-Phosphonoacetyl-L-ornithine
-
 Sus scrofa