Literature summary for 2.1.3.7 extracted from

Chary, V.K.; de la Fuente, J.L.; Liras, P.; Martin, J.F.
Amy as a reporter gene for promoter activity in Nocardia lactamdurans: comparison of promoters of the cephamycin cluster (1997), Appl. Environ. Microbiol., 63, 2977-2982.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
carbamoyl phosphate + a 3-hydroxymethyl ceph-3-em-4-carboxylate	Amycolatopsis lactamdurans	the cmcH gene - encoding 3-hydroxymethylcephem carbamoyltransferase - upstream region does not contain a functional promoter, suggesting that cmcH is transcribed as a part of a polycistronic mRNA	phosphate + a 3-carbamoyloxymethylcephem	-	?

Organism

Organism	UniProt	Comment	Textmining
Amycolatopsis lactamdurans	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
carbamoyl phosphate + a 3-hydroxymethyl ceph-3-em-4-carboxylate	the cmcH gene - encoding 3-hydroxymethylcephem carbamoyltransferase - upstream region does not contain a functional promoter, suggesting that cmcH is transcribed as a part of a polycistronic mRNA	Amycolatopsis lactamdurans	phosphate + a 3-carbamoyloxymethylcephem	-	?

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Release 2023.1 (January 2023)