Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ornithine | competitive inhibition | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
52000 | 56000 | wild-type enzyme AT, mutant ATdelta11, mutant ATdeltaM302, gel filtration | Homo sapiens |
89200 | - |
mutant ATDELTA11, calculated molecular mass | Homo sapiens |
90000 | - |
mutant ATDELTAM302, sedimentation analysis | Homo sapiens |
90100 | - |
mutant ATDELTA11, sedimentation analysis | Homo sapiens |
91600 | - |
mutant ATDELTAM302, calculated molecular mass | Homo sapiens |
91800 | - |
wild-type enzyme AT, calculated molecular mass | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arginine + glycine | Homo sapiens | - |
L-ornithine + guanidinoacetate | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
human | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
arginine + 3-aminopropionic acid | - |
Homo sapiens | 3-guanidinopropionic acid + ornithine | - |
? | |
arginine + 4-aminobutyric acid | - |
Homo sapiens | 4-guanidinobutyric acid + ornithine | - |
? | |
arginine + delta-aminovaleric acid | - |
Homo sapiens | delta-guanidinovaleric acid + ornithine | - |
? | |
arginine + gamma-aminobutyric acid | - |
Homo sapiens | gamma-guanidinobutyric acid + ornithine | - |
? | |
canavanine + glycine | - |
Homo sapiens | guanidinoacetate + canaline | - |
r | |
canavanine + ornithine | - |
Homo sapiens | arginine + canaline | - |
r | |
hydroxyguanidine + glycine | - |
Homo sapiens | hydroxylamine + guanidinoacetate | - |
? | |
L-alanine + glycine | - |
Homo sapiens | ? | - |
? | |
L-aminobutyric acid + glycine | - |
Homo sapiens | ? | - |
? | |
L-arginine + glycine | - |
Homo sapiens | L-ornithine + guanidinoacetate | - |
r | |
L-norvaline + glycine | - |
Homo sapiens | ? | - |
? | |
additional information | homoarginine, alpha-amino-gamma-guanidinobutyric acid and alpha-amino-beta-guanidinopropionic acid are not substrates | Homo sapiens | ? | - |
? |