Application | Comment | Organism |
---|---|---|
medicine | upregulation of TKTL1 in the metabolism of astrocytic gliomas with different degrees of malignancy. Percentage of positive cells for TKTL1 and p-Akt are significantly correlated. These observations can lead to additional therapeutic options targeting a specific blockade of TKTL1 enzyme activity | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
60000 | - |
smaller splice variant, Western blot analysis | Homo sapiens |
70000 | - |
larger splice variant, Western blot analysis | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P51854 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
glioblastoma multiforme cell | compared with grades II and III astrocytic gliomas, glioblastoma multiformes show higher expression of TKTL1 | Homo sapiens | - |
additional information | TKTL1 is significantly overexpressed in tumors of astrocytic gliomas. Tumor grade significantly correlates with expression of TKTL1 | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
TKTL1 | - |
Homo sapiens |
transketolase-like 1 | - |
Homo sapiens |