Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | thiamine diphosphate affinity to the enzymes active sites is higher in the presence of Ca2+ than in the presence of Mg2+ | Saccharomyces cerevisiae | |
Mg2+ | thiamine diphosphate affinity to the enzymes active sites is higher in the presence of Ca2+ than in the presence of Mg2+ | Saccharomyces cerevisiae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | transketolase reaction is irreversible when hydroxypyruvate is used as a donor substrate | Saccharomyces cerevisiae | ? | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
thiamine diphosphate | two-step mechanism of interaction of thiamine diphosphate with transketolase. Formation of inactive intermediate complex followed by its transformation into catalytically active holoenzyme | Saccharomyces cerevisiae |