Application | Comment | Organism |
---|---|---|
medicine | both TKTL1 and p-Akt play an important role in the progression of cervical neoplasia, which may be due to their impact on glycolysis. Intensity of the expression of TKTL1 and the oncogene p-Akt increases significantly with an increase in the histopathological grade of cervical tissues. TKTL1 and p-Akt can be possibly valuable targets for nontoxic antitumor therapeutic approaches, especially in cervical precancerous lesions and cancer | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Homo sapiens | 5737 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P51854 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cervical cell line | - |
Homo sapiens | - |
additional information | LGSIL cell, low-grade squamous intraepithelial lesions, low expression of TKTL1. HGSIL cell, high-grade squamous intraepithelial lesions, high expression of TKTL1. ISCC cell, invasive squamous cell carcinomas, highest expression of TKTL1 | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
TKTL1 | - |
Homo sapiens |
transketolase-like 1 | - |
Homo sapiens |
transketolase-like enzyme 1 | - |
Homo sapiens |