Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the enzyme is part of a supramolecular complex containing glucose-6-phosphate dehydrogenase, responsible for substrate channeling, in female neutrophils that undergoes retrograde trafficking during pregnancy, trafficking occurs in nonpregnant women, the key regulatory enzyme in the nonoxidative branch of the hexose monophosphate shunt, is not in close physical proximity with lactate dehydrogenase, TALases retrograde motion contributes to uncoupling the shunt from its source of glucose-6-phosphate at the plasma membrane, thereby blunting NADPH2 production and downstream oxidant production by neutrophils, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Homo sapiens | - |
pregnant and nonpregnant women | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neutrophil | in neutrophils from nonpregnant individuals, enzyme undergoes anterograde trafficking, whereas retrograde trafficking is found during pregnacy. Trafficking involves microtubules | Homo sapiens | - |
neutrophil | the transaldolase is part of a supramolecular complex containing glucose-6-phosphate dehydrogenase in neutrophils that undergoes retrograde trafficking during pregnancy, enzyme trafficking, overview | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme is part of a supramolecular complex containing glucose-6-phosphate dehydrogenase, responsible for substrate channeling, in female neutrophils that undergoes retrograde trafficking during pregnancy, trafficking occurs in nonpregnant women, the key regulatory enzyme in the nonoxidative branch of the hexose monophosphate shunt, is not in close physical proximity with lactate dehydrogenase, TALases retrograde motion contributes to uncoupling the shunt from its source of glucose-6-phosphate at the plasma membrane, thereby blunting NADPH2 production and downstream oxidant production by neutrophils, overview | Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | enzyme forms a complex with glucose-6-phosphate dehydrogenase | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
TALase | - |
Homo sapiens |
transaldolase | - |
Homo sapiens |