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Literature summary for 2.2.1.5 extracted from
- Inhibition of the alpha-ketoglutarate dehydrogenase complex from baker's yeast by acetaldehyde and glyoxylate (1972), Agric. Biol. Chem., 36, 1249-1251.
No PubMed abstract available
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | part of alpha-ketoglutarate dehydrogenase complex | Saccharomyces cerevisiae | 5739 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-oxoglutarate + acetaldehyde | - |
Saccharomyces cerevisiae | 5-hydroxy-4-oxohexanoate + CO2 | - |
? |  |
| 2-oxoglutarate + glyoxylate | - |
Saccharomyces cerevisiae | 2-hydroxy-3-oxohexandioate + CO2 | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
enzyme assay at | Saccharomyces cerevisiae |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
enzyme assay at | Saccharomyces cerevisiae |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| thiamine diphosphate | - |
Saccharomyces cerevisiae | |
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Release 2023.1 (January 2023)
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