Application | Comment | Organism |
---|---|---|
medicine | involved in renal stone formation, decreased activity due to thiamine deficiency may increase oxalate excretion by 35% | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
rat | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Rattus norvegicus | - |
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
thiamine deficiency decreases specific activity | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-oxoglutarate + glyoxylate | - |
Rattus norvegicus | 2-hydroxy-3-oxohexandioate + CO2 | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
thiamine diphosphate | deficiency may lead to hyperoxaluria and glyoxylate excretion | Rattus norvegicus |