Crystallization (Comment) | Organism |
---|---|
in complex with inhibitors N-[(4-methylpyrimidin-2-yl)carbamoyl]-2-nitrobenzenesulfonamide and methyl 2-([(4-methylpyrimidin-2-yl)carbamoyl]sulfamoyl)benzoate, to 3.0 A and 2.8 A resolution, respectively. In both complexes, the inhibitors are bound in the tunnel leading to the active site, such that the sole substituent of the heterocyclic ring is buried deepest and oriented towards the thiamine diphosphate. The cofactor is intact and present most likely as the hydroxylethyl intermediate | Arabidopsis thaliana |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
methyl 2-([(4-methylpyrimidin-2-yl)carbamoyl]sulfamoyl)benzoate | - |
Arabidopsis thaliana | |
N-[(4-methylpyrimidin-2-yl)carbamoyl]-2-nitrobenzenesulfonamide | - |
Arabidopsis thaliana |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | P17597 | - |
- |