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Literature summary for 2.3.1.1 extracted from

  • Rajagopal, B.S.; Deponte, J.; Tuchman, M.; Malamy, M.H.
    Use of inducible feedback-resistant N-acetylglutamate synthetase (argA) genes for enhanced arginine biosynthesis by genetically engineered Escherichia coli K-12 strains (1998), Appl. Environ. Microbiol., 64, 1805-1811.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
cloning of N-acetylglutamate synthase gene argA and a mutant gene fbr-argA responsible for arginine feedback resistance Escherichia coli

Protein Variants

Protein Variants Comment Organism
G287S arginine feedback resistant mutant enzyme Escherichia coli
H15Y arginine feedback resistant mutant enzyme Escherichia coli
Q432R arginine feedback resistant mutant enzyme Escherichia coli
R58H arginine feedback resistant mutant enzyme Escherichia coli
S54N arginine feedback resistant mutant enzyme Escherichia coli
Y19C arginine feedback resistant mutant enzyme Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli P0A6C5
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + L-glutamate
-
 Escherichia coli CoA + N-acetyl-L-glutamate
-
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