Literature summary for 2.3.1.101 extracted from

Pomper, B.K.; Saurel, O.; Milon, A.; Vorholt, J.A.
Generation of formate by the formyltransferase/hydrolase complex (Fhc) from Methylobacterium extorquens AM1 (2002), FEBS Lett., 523, 133-137.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
formylmethanofuran + 5,6,7,8-tetrahydromethanopterin	Methylorubrum extorquens	-	methanofuran + N5-formyl-5,6,7,8-tetrahydromethanopterin	-	r

Organism

Organism	UniProt	Comment	Textmining
Methylorubrum extorquens	-	-	-

Reaction

Reaction	Comment	Organism	Reaction ID
formylmethanofuran + 5,6,7,8-tetrahydromethanopterin = methanofuran + 5-formyl-5,6,7,8-tetrahydromethanopterin	enzyme complex renamed formyltransferase/hydrolase complex	Methylorubrum extorquens	a
formylmethanofuran + 5,6,7,8-tetrahydromethanopterin = methanofuran + 5-formyl-5,6,7,8-tetrahydromethanopterin	pathway via enzyme complex	Methylorubrum extorquens	a

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
formylmethanofuran + 5,6,7,8-tetrahydromethanopterin	-	Methylorubrum extorquens	methanofuran + N5-formyl-5,6,7,8-tetrahydromethanopterin	-	r
additional information	formyltransferase/hydrolase complex also catalyzes the hydrolysis of formyl-methanofuran to formate	Methylorubrum extorquens	?	-	?

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Release 2023.1 (January 2023)