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Literature summary for 2.3.1.108 extracted from

  • Howes, S.C.; Alushin, G.M.; Shida, T.; Nachury, M.V.; Nogales, E.
    Effects of tubulin acetylation and tubulin acetyltransferase binding on microtubule structure (2014), Mol. Biol. Cell, 25, 257-266.
    View publication on PubMedView publication on EuropePMC

Crystallization (Commentary)

Crystallization (Comment) Organism
no significant changes are observed in the architecture of microtubules or the conformation of tu­bulin upon acetylation, based on protofilament distributions or microtubule helical lattice parameters. No clear differences in tubulin structure are detected between cryo-EM reconstructions of maxi­mally deacetylated or acetylated microtubules. The effect of acetyla­tion must be highly localized and affect interaction with proteins that bind directly to the lumen of the microtubule. alpha-TAT1 is able to interact with the outside of the microtubule, at least partly through the tubulin C-termini Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q5SQI0
-
-

Synonyms

Synonyms Comment Organism
ATAT1
-
Homo sapiens