Literature summary for 2.3.1.12 extracted from

Mande, S.S.; Sarfaty, S.; Allen, M.D.; Perham, R.N.; Hol, W.G.J.
Protein-protein interactions in the pyruvate dehydrogenase multienzyme complex: dihydrolipoamide dehydrogenase complexed with the binding domain of dihydrolipoamide acetyltransferase (1996), Structure, 4, 277-286.

Search for more literature for 2.3.1.12

Crystallization (Commentary)

Crystallization (Comment)	Organism
E3 dimer with E2 and a small binding domain E2BD, hanging drop vapor diffusion method	Geobacillus stearothermophilus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
dihydrolipoamide + acetyl-CoA	Geobacillus stearothermophilus	-	S-acetyldihydrolipoamide + CoA	-	?

Organism

Organism	UniProt	Comment	Textmining
Geobacillus stearothermophilus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
dihydrolipoamide + acetyl-CoA	-	Geobacillus stearothermophilus	S-acetyldihydrolipoamide + CoA	-	?

Subunits

Subunits	Comment	Organism
polymer	60 polypeptide chains, crystal structure	Geobacillus stearothermophilus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)