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Literature summary for 2.3.1.127 extracted from

  • Seymour, M.A.; Millburn, P.; Tait, G.H.
    Renal biosynthesis of ornithuric acid in quail (1987), Biochem. Soc. Trans., 15, 1108-1109.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
isoleucine markedly inhibition when arginine but not when ornithine is the acyl acceptor Coturnix japonica

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion renal and hepatic Coturnix japonica 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
benzoyl-CoA + L-ornithine Coturnix japonica
-
CoA + N2,N5-dibenzoyl-L-ornithine i.e. ornithuric acid ?

Organism

Organism UniProt Comment Textmining
Anser sp.
-
goose
-
Cairina moschata
-
muscovy duck
-
Coturnix japonica
-
japanese quail
-
Gallus gallus
-
chicken
-
Meleagris gallopavo
-
turkey
-

Purification (Commentary)

Purification (Comment) Organism
partial Coturnix japonica

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
Gallus gallus
-
kidney
-
Meleagris gallopavo
-
kidney
-
Anser sp.
-
kidney
-
Cairina moschata
-
kidney
-
Coturnix japonica
-
liver only low levels of activity Coturnix japonica
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0045
-
-
Coturnix japonica

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzoyl-CoA + arginine
-
Coturnix japonica CoA + ornithuric acid
-
?
benzoyl-CoA + L-ornithine
-
Coturnix japonica CoA + N2,N5-dibenzoyl-L-ornithine i.e. ornithuric acid ?
benzoyl-CoA + lysine weak acyl acceptor in vitro Coturnix japonica ?
-
?
additional information glycine, taurine, glutamine and glutamic acid are not substrates Coturnix japonica ?
-
?