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Literature summary for 2.3.1.13 extracted from

  • van der Sluis, R.; Badenhorst, C.P.; Erasmus, E.; van Dyk, E.; van der Westhuizen, F.H.; van Dijk, A.A.
    Conservation of the coding regions of the glycine N-acyltransferase gene further suggests that glycine conjugation is an essential detoxification pathway (2015), Gene, 571, 126-134.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
F168L the mutation has a negative effect on the enzyme activity Homo sapiens
N156S the mutation has a negative effect on the enzyme activity Homo sapiens
Q61L the mutation has a negative effect on the enzyme activity Homo sapiens
R131H the mutation has a negative effect on the enzyme activity Homo sapiens
R199C the mutation has a negative effect on the enzyme activity Homo sapiens
S17T the mutation has a negative effect on the enzyme activity Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acyl-CoA + glycine Homo sapiens
-
CoA + N-acylglycine
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q6IB77
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + glycine
-
Homo sapiens CoA + N-acylglycine
-
?

Synonyms

Synonyms Comment Organism
GlyAT
-
Homo sapiens