Cloned (Comment) | Organism |
---|---|
expression of mitochondrial acyltransferase in Sf21 insect cells | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2,3-Butanedione | 5 mM, 54% and 21% inhibition of microsomal and mitochondrial acyltransferase respectively | Rattus norvegicus | |
aminophenylboronate | mixed-type inhibition of microsomal and mitochondrial acyltransferase vs. glycerol 3-phosphate | Rattus norvegicus | |
diethyldicarbonate | 0.3 mM, approx. 67% inhibition of microsomal acyltransferase, approx. 40% inhibition of mitochondrial acyltransferase, approx. 60% inhibition of recombinant mitochondrial acyltransferase, activity is restored to approx 50% by hydroxylamine | Rattus norvegicus | |
Phenylglyoxal | 1 mM, 88% and 59% inhibition of microsomal and mitochondrial acyltransferase, respectively; 1 mM, 88% and 59% inhibition of microsomal and mitochondrial acyltransferase, respectively | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Rattus norvegicus | P97564 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
2.9 | - |
aminophenylboronate | microsomal acyltransferase | Rattus norvegicus | |
8.2 | - |
aminophenylboronate | mitochondrial acyltransferase | Rattus norvegicus | |
10.3 | - |
aminophenylboronate | recombinant mitochondrial acyltransferase | Rattus norvegicus |