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Literature summary for 2.3.1.156 extracted from

  • Klingauf, P.; Beuerle, T.; Mellenthin, A.; El-Moghazy, S.A.; Boubakir, Z.; Beerhues, L.
    Biosynthesis of the hyperforin skeleton in Hypericum calycinum cell cultures (2005), Phytochemistry, 66, 139-145.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
isobutyryl-CoA + 3 malonyl-CoA Hypericum calycinum enzyme is involved in formation of the hyperforin skeleton of Hypericum calycinum phloroisobutyrophenone + 3 CO2 + 4 CoA
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Organism

Organism UniProt Comment Textmining
Hypericum calycinum
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Purification (Commentary)

Purification (Comment) Organism
separation of benzophenone synthase, isobutyrophenone synthase, and chalcone synthase activities Hypericum calycinum

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
isobutyryl-CoA + 3 malonyl-CoA
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Hypericum calycinum phloroisobutyrophenone + 3 CO2 + 4 CoA
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?
isobutyryl-CoA + 3 malonyl-CoA enzyme is involved in formation of the hyperforin skeleton of Hypericum calycinum Hypericum calycinum phloroisobutyrophenone + 3 CO2 + 4 CoA
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?