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Literature summary for 2.3.1.162 extracted from
- Regioselectivity of taxoid-O-acetyltransferases: heterologous expression and characterization of a new taxadien-5alpha-ol-O-acetyltransferase (2004), Arch. Biochem. Biophys., 430, 237-246.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.005 | - |
taxadien-5alpha-ol | - |
Taxus cuspidata |  |
| 0.0086 | - |
taxadien-5alpha-ol | - |
Taxus cuspidata | |
| 0.0129 | - |
taxadien-2alpha,5alpha,10beta-triol | - |
Taxus cuspidata | |
| 0.0173 | - |
taxadien-5alpha,9alpha,10beta,13alpha-tetraol | - |
Taxus cuspidata | |
| 0.0239 | - |
taxadien-2alpha,5alpha-diol | - |
Taxus cuspidata | |
| 0.0415 | - |
taxadien-2alpha,5alpha,10beta-triol | - |
Taxus cuspidata | |
| 0.0453 | - |
taxadien-5alpha,9alpha,10beta,13alpha-tetraol | - |
Taxus cuspidata | |
| 0.0835 | - |
taxadien-5alpha-acetoxy-9alpha,10beta,13alpha-triol | - |
Taxus cuspidata | |
| 0.2794 | - |
taxadien-5alpha-acetoxy-9alpha,10beta,13alpha-triol | - |
Taxus cuspidata | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Taxus cuspidata | Q5Y9C6 | TAX19 acetyltransferase | - |
| Taxus cuspidata | Q5Y9C7 | taxoid-O-acetyltransferase; TAX1 acetyltransferase | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2 acetyl-CoA + taxadien-5alpha-acetoxy-9alpha,10beta,13alpha-triol | - |
Taxus cuspidata | 2 CoA + taxadien-5alpha,9alpha,10beta-triacetoxy-13alpha-ol | - |
? | |
| acetyl-CoA + taxadien-2alpha,5alpha,10beta-triol | - |
Taxus cuspidata | CoA + taxadien-10beta-acetoxy-2alpha,5alpha-diol | - |
? | |
| acetyl-CoA + taxadien-2alpha,5alpha,10beta-triol | - |
Taxus cuspidata | CoA + taxadien-5alpha-acetoxy-2alpha,10beta-diol | - |
? | |
| acetyl-CoA + taxadien-2alpha,5alpha-diol | - |
Taxus cuspidata | CoA + taxadien-5alpha-acetoxy-2alpha-ol | - |
? | |
| acetyl-CoA + taxadien-5alpha,9alpha,10beta,13alpha-tetraol | - |
Taxus cuspidata | CoA + taxadien-10beta-acetoxy-5alpha,9alpha,13alpha-triol | - |
? | |
| acetyl-CoA + taxadien-5alpha,9alpha,10beta,13alpha-tetraol | - |
Taxus cuspidata | CoA + taxadien-13alpha-acetoxy-5alpha,9alpha,10beta-triol | - |
? | |
| acetyl-CoA + taxadien-5alpha-acetoxy-9alpha,10beta,13alpha-triol | - |
Taxus cuspidata | CoA + taxadien-5alpha,13alpha-diacetoxy-9alpha,10beta-diol | - |
? | |
| acetyl-CoA + taxadien-5alpha-ol | - |
Taxus cuspidata | CoA + taxadien-5alpha-yl acetate | - |
? | |
| additional information | no detectable activity with taxadien-2alpha,5alpha-diol | Taxus cuspidata | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TAX1 acetyltransferase | - |
Taxus cuspidata |
| TAX19 acetyltransferase | - |
Taxus cuspidata |
| taxoid-O-acetyltransferase | - |
Taxus cuspidata |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 4.28 | - |
taxadien-5alpha-ol | - |
Taxus cuspidata | |
| 5.77 | - |
taxadien-2alpha,5alpha,10beta-triol | - |
Taxus cuspidata | |
| 11.91 | - |
taxadien-5alpha,9alpha,10beta,13alpha-tetraol | - |
Taxus cuspidata | |
| 15.47 | - |
taxadien-5alpha,9alpha,10beta,13alpha-tetraol | - |
Taxus cuspidata | |
| 27.92 | - |
taxadien-2alpha,5alpha,10beta-triol | - |
Taxus cuspidata | |
| 29.59 | - |
taxadien-5alpha-ol | - |
Taxus cuspidata | |
| 52.13 | - |
taxadien-2alpha,5alpha-diol | - |
Taxus cuspidata | |
| 145 | - |
taxadien-5alpha-acetoxy-9alpha,10beta,13alpha-triol | - |
Taxus cuspidata | |
| 297.9 | - |
taxadien-5alpha-acetoxy-9alpha,10beta,13alpha-triol | - |
Taxus cuspidata | |
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