Literature summary for 2.3.1.165 extracted from

Moriguchi, T.; Ebizuka, Y.; Fujii, I.
Analysis of subunit interactions in the iterative type I polyketide synthase ATX from Aspergillus terreus (2006), Chembiochem, 7, 1869-1874.

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Protein Variants

Protein Variants	Comment	Organism
additional information	N-terminal deletion mutant ATXN1 lacking 44 amino acids, catalytically active. N-terminal deletion mutant ATXN2 lacking 81 amino acids including part of the ketosynthase domain, loss of catalytic activity. Both ATXC1 lacking 9 carboxyterminal amino acids and ATXC2 lacking 21 carboxyterminal amino acids including part of the conserved acyl carrier protein domain are inactive. Coexpression of inactive mutants ATXN2 with ATXC1 or ATXC2 results in restauration of activity. Identification of an interdomain region required for the formation of the active reaction center	Aspergillus terreus

Organism

Organism	UniProt	Comment	Textmining
Aspergillus terreus	-	recombinant expression in Saccharomyces cerevisiae	-

Synonyms

Synonyms	Comment	Organism
ATX	-	Aspergillus terreus

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Release 2023.1 (January 2023)