KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.28 | - |
acetyl-CoA | exchange activity: C14 from the carboxyl group of acetyl-CoA with C12 from CO | Carboxydothermus hydrogenoformans |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Carboxydothermus hydrogenoformans | 5737 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Cu | the Ni in cluster A can be replaced by Cu yielding an inactive form of the acetyl-CoA synthase | Carboxydothermus hydrogenoformans | |
Ni | the functional cluster A of ACSCh contains a Ni-Ni-[4Fe-4S] site, in which the position proximal and distal to the cubane are occupied by Ni ions | Carboxydothermus hydrogenoformans | |
Zn | the Ni in cluster A can be replaced by Zn yielding an inactive form of the acetyl-CoA synthase | Carboxydothermus hydrogenoformans |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
81700 | - |
gel filtration | Carboxydothermus hydrogenoformans |
82900 | - |
1 * 82900, the enzyme exists as a monomer as well as in a 1:1 molar complex with the 73300 Da CO dehydrogenase III, SDS-PAGE | Carboxydothermus hydrogenoformans |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Carboxydothermus hydrogenoformans | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme catalyzes the exchange of 14C from the carboxyl group of acetyl-CoA with 12C from CO | Carboxydothermus hydrogenoformans | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 82900, the enzyme exists as a monomer as well as in a 1:1 molar complex with the 73300 Da CO dehydrogenase III, SDS-PAGE | Carboxydothermus hydrogenoformans |
Synonyms | Comment | Organism |
---|---|---|
ACS/CODH | - |
Carboxydothermus hydrogenoformans |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
70 | - |
exchange activity: C14 from the carboxyl group of acetyl-CoA with C12 from CO | Carboxydothermus hydrogenoformans |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6 | - |
exchange activity: C14 from the carboxyl group of acetyl-CoA with C12 from CO | Carboxydothermus hydrogenoformans |