Cloned (Comment) | Organism |
---|---|
expression in Streptomyces lividans | Streptomyces peucetius |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
37189 | - |
1 * 37189, recombinant enzyme, mass spectrometry | Streptomyces peucetius |
38000 | - |
gel filtration, recombinant enzyme | Streptomyces peucetius |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
propionyl-CoA + malonyl-[acyl-carrier protein] | Streptomyces peucetius | the enzyme specifies the propionate-starter unit for type II polyketide biosynthesis | 3-oxo-valeryl-[acyl-carrier protein] + CoA + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces peucetius | - |
gene dpsC | - |
Purification (Comment) | Organism |
---|---|
recombinant enzyme from Streptomyces lividans by ammonium sulfate fractionation, gel filtration, ion exchange and hydrophobic interaction chromatography | Streptomyces peucetius |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | no activity with acetyl-CoA, malonyl-CoA, and 2-methylmalonyl-CoA as primer for elongation of fatty acids, the enzyme shows also acyl-CoA:ACP transacylase activity for transfer of propionate to ACP | Streptomyces peucetius | ? | - |
? | |
propionyl-CoA + malonyl-[acyl-carrier protein] | the enzyme specifies the propionate-starter unit for type II polyketide biosynthesis | Streptomyces peucetius | 3-oxo-valeryl-[acyl-carrier protein] + CoA + CO2 | - |
? | |
propionyl-CoA + malonyl-[acyl-carrier protein] | intermediate binding of propionyl to the enzyme at Ser118 | Streptomyces peucetius | 3-oxo-valeryl-[acyl-carrier protein] + CoA + CO2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 37189, recombinant enzyme, mass spectrometry | Streptomyces peucetius |
Synonyms | Comment | Organism |
---|---|---|
beta-ketoacyl:acyl carrier protein synthase III | - |
Streptomyces peucetius |
DpsC | - |
Streptomyces peucetius |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
22 | - |
assay at room temperature | Streptomyces peucetius |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.2 | - |
assay at | Streptomyces peucetius |