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Literature summary for 2.3.1.184 extracted from

  • Hansen, M.R.; Jakobsen, T.H.; Bang, C.G.; Cohrt, A.E.; Hansen, C.L.; Clausen, J.W.; Le Quement, S.T.; Tolker-Nielsen, T.; Givskov, M.; Nielsen, T.E.
    Triazole-containing N-acyl homoserine lactones targeting the quorum sensing system in Pseudomonas aeruginosa (2015), Bioorg. Med. Chem., 23, 1638-1650.
    View publication on PubMed
Search for more literature for 2.3.1.184

Inhibitors

Inhibitors Comment Organism Structure
2-(4-cyclopentyl-1H-1,2,3-triazol-1-yl)-N-[(3S)-2-oxotetrahydrofuran-3-yl]acetamide IC50 value for growth of Escherichia coli 0.050 mM Escherichia coli
2-(4-cyclopentyl-1H-1,2,3-triazol-1-yl)-N-[(3S)-2-oxotetrahydrofuran-3-yl]acetamide IC50 value for growth of Pseudomonas aeruginosa 0.610 mM Pseudomonas aeruginosa
2-(4-hexyl-1H-1,2,3-triazol-1-yl)-N-[(3S)-2-oxotetrahydrofuran-3-yl]acetamide IC50 value for growth of Escherichia coli 0.578 mM Escherichia coli
2-(4-hexyl-1H-1,2,3-triazol-1-yl)-N-[(3S)-2-oxotetrahydrofuran-3-yl]acetamide IC50 value for growth of Pseudomonas aeruginosa 0.425 mM Pseudomonas aeruginosa
3-[4-(3-formylphenyl)-1H-1,2,3-triazol-1-yl]-N-[(3S)-2-oxotetrahydrofuran-3-yl]propanamide IC50 value for growth of Escherichia coli 0.005 mM Escherichia coli
3-[4-(3-formylphenyl)-1H-1,2,3-triazol-1-yl]-N-[(3S)-2-oxotetrahydrofuran-3-yl]propanamide IC50 value for growth of Pseudomonas aeruginosa 0.381 mM Pseudomonas aeruginosa

Organism

Organism UniProt Comment Textmining
Escherichia coli
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Pseudomonas aeruginosa
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