Any feedback?
Literature summary for 2.3.1.199 extracted from
- Substrate specificity of Arabidopsis 3-ketoacyl-CoA synthases (2006), Biochem. Biophys. Res. Commun., 346, 583-590.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Saccharomyces cerevisiae | Arabidopsis thaliana |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arabidopsis thaliana | - |
ecotype Columbia | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| the His6-tagged enzyme is purified by Ni2+-pentadentate chelator affinity matrix column chromatography | Arabidopsis thaliana |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| arachidoyl-CoA + malonyl-CoA | best substrate for At4g34510 | Arabidopsis thaliana | ? | - |
? |  |
| additional information | At1g01120 (KCS1) and At2g26640 have broad substrate specificities when assayed with saturated and monounsaturated C16 to C24 acyl-CoAs while At4g34510 is specific for saturated fatty acyl-CoA substrates. KCS1 is most active with palmitic acid, palmitoleic acid, stearic acid, and arachidic acid but has very little activity with oleic acid and acyl chains longer than C20. At4g34510 is specific for saturated acyl-CoAs up to C22. FAE1 uses palmitic acid, palmitoleic acid, stearic acid, oleic acid, arachidic acid, 20:1, behenic acid, erucic acid, and lignoceric acid as substratesis and is specific for acyl-CoAs of 16 and 18 carbons in length | Arabidopsis thaliana | ? | - |
? | |
| palmitoyl-CoA + malonyl-CoA | best substrate for KCS1 | Arabidopsis thaliana | ? | - |
? | |
| stearoyl-CoA + malonyl-CoA | best substrate for At2g26640 and FAE1 | Arabidopsis thaliana | ? | - |
? | |
| very-long-chain acyl-CoA + malonyl-CoA | - |
Arabidopsis thaliana | CoA + very-long-chain 3-oxoacyl-CoA + CO2 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 3-ketoacyl-CoA synthase | - |
Arabidopsis thaliana |
| At1g01120 | - |
Arabidopsis thaliana |
| At2g26640 | - |
Arabidopsis thaliana |
| FAE1 | - |
Arabidopsis thaliana |
| fatty acid elongase 1 | - |
Arabidopsis thaliana |
| KCS | - |
Arabidopsis thaliana |
| Kcs1 | - |
Arabidopsis thaliana |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
