Literature summary for 2.3.1.20 extracted from

Oh, W.K.; Lee, C.; Seo, J.H.; Chung, M.Y.; Cui, L.; Fomum, Z.T.; Kang, J.S.; Lee, H.S.
Diacylglycerol acyltransferase-inhibitory compounds from Erythrina senegalensis (2009), Arch. Pharm. Res., 32, 43-47.

Search for more literature for 2.3.1.20

Inhibitors

Inhibitors	Comment	Organism	Structure
6,8-diprenylgenistein	IC50: 0.0067 mg/ml	Rattus norvegicus
8-prenylleutone	IC50: 0.015 mg/ml	Rattus norvegicus
alpinumisoflavone	23% inhibition at 0.0125 mg/ml	Rattus norvegicus
auriculatin	IC50: 0.0072 mg/ml	Rattus norvegicus
derrone	IC50: 0.0151 mg/ml	Rattus norvegicus
erysenegalensein D	IC50: 0.0015 mg/ml	Rattus norvegicus
erysenegalensein N	28% inhibition at 0.0125 mg/ml	Rattus norvegicus
erysenegalensein O	IC50: 0.0011 mg/ml	Rattus norvegicus
kurarinone	IC50: 0.0048 mg/ml	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Rattus norvegicus	-

Synonyms

Synonyms	Comment	Organism
diacylglycerol acyltransferase	-	Rattus norvegicus

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
additional information	-	kurarione IC50: 0.0048 mg/ml, 8-prenylleutone IC50: 0.015 mg/ml, auriculatin IC50: 0.0072 mg/ml, erysenegalensein O IC50: 0.0011 mg/ml, erysenegalensein D IC50: 0.0015 mg/ml, erysenegalensein N: 28% inhibition at 0.0125 mg/ml, derrone IC50: 0.0151 mg/ml, alpinumisoflavone: 23% inhibition at 0.0125 mg/ml, 6,8-diprenylgenistein IC50: 0.0067 mg/ml	Rattus norvegicus	additional information

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Release 2023.1 (January 2023)