Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.1.21 extracted from

  • Woeltje, K.F.; Esser, V.; Weis, B.C.; Cox, W.F.; Schroeder, J.G.; Liao, S.L.; Foster, D.W.; McGarry, J.D.
    Inter-tissue and inter-species characteristics of the mitochondrial carnitine palmitoyltransferase enzyme system (1990), J. Biol. Chem., 265, 10714-10719.
    View publication on PubMed
Search for more literature for 2.3.1.21

Inhibitors

Inhibitors Comment Organism Structure
CoA esters of certain oxirane carboxylic acids irreversible, CPT I but not CPT II Homo sapiens
CoA esters of certain oxirane carboxylic acids irreversible, CPT I but not CPT II Mus musculus
CoA esters of certain oxirane carboxylic acids irreversible, CPT I but not CPT II Platyrrhini
CoA esters of certain oxirane carboxylic acids irreversible, CPT I but not CPT II Rattus norvegicus
malonyl-CoA CPT I; CPT II not inhibited; reversible inhibition Homo sapiens
malonyl-CoA CPT I; CPT II not inhibited; reversible inhibition Mus musculus
malonyl-CoA CPT I; CPT II not inhibited; reversible inhibition Platyrrhini
malonyl-CoA CPT I; CPT II not inhibited; reversible inhibition Rattus norvegicus
octyl glucoside complete loss of CPT I activity, no loss of CPT II activity Homo sapiens
octyl glucoside complete loss of CPT I activity, no loss of CPT II activity Mus musculus
octyl glucoside complete loss of CPT I activity, no loss of CPT II activity Platyrrhini
octyl glucoside complete loss of CPT I activity, no loss of CPT II activity Rattus norvegicus
Triton X-100 complete loss of CPT I activity, no loss of CPT II activity Homo sapiens
Triton X-100 complete loss of CPT I activity, no loss of CPT II activity Mus musculus
Triton X-100 complete loss of CPT I activity, no loss of CPT II activity Platyrrhini
Triton X-100 complete loss of CPT I activity, no loss of CPT II activity Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Mus musculus 5739
-
mitochondrion
-
 Homo sapiens 5739
-
mitochondrion
-
 Rattus norvegicus 5739
-
mitochondrion
-
 Platyrrhini 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acyl-CoA + L-carnitine Mus musculus
-
 CoA + L-acylcarnitine
-
 ?
acyl-CoA + L-carnitine Homo sapiens
-
 CoA + L-acylcarnitine
-
 ?
acyl-CoA + L-carnitine Rattus norvegicus
-
 CoA + L-acylcarnitine
-
 ?
acyl-CoA + L-carnitine Platyrrhini
-
 CoA + L-acylcarnitine
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-
Platyrrhini
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
 Mus musculus
-
heart
-
 Homo sapiens
-
heart
-
 Rattus norvegicus
-
liver
-
 Mus musculus
-
liver
-
 Homo sapiens
-
liver
-
 Rattus norvegicus
-
liver
-
 Platyrrhini
-
skeletal muscle
-
 Mus musculus
-
skeletal muscle
-
 Homo sapiens
-
skeletal muscle
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + L-carnitine
-
 Mus musculus CoA + L-acylcarnitine
-
 ?
acyl-CoA + L-carnitine
-
 Homo sapiens CoA + L-acylcarnitine
-
 ?
acyl-CoA + L-carnitine
-
 Rattus norvegicus CoA + L-acylcarnitine
-
 ?
acyl-CoA + L-carnitine
-
 Platyrrhini CoA + L-acylcarnitine
-
 ?