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Literature summary for 2.3.1.21 extracted from

  • Kopec, B.; Fritz, I.B.
    Comparison of properties of carnitine palmitoyltransferase I with those of carnitine palmitoyltransferase II, and preparation of antibodies to carnitine palmitoyltransferases (1973), J. Biol. Chem., 248, 4069-4074.
    View publication on PubMed
Search for more literature for 2.3.1.21

Inhibitors

Inhibitors Comment Organism Structure
Short chain-length fatty acylcarnitine derivatives
-
 Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
150000
-
 CPT I and II, gel filtration Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acyl-CoA + L-carnitine Rattus norvegicus
-
 CoA + L-acylcarnitine
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
CPT II, partial Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + L-carnitine
-
 Rattus norvegicus CoA + L-acylcarnitine
-
 ?
acyl-CoA + L-carnitine CPT II shows greater chain-length substrate specificity for transfer of long chain fatty acyl groups from (-)-acylcarnitine derivatives to CoA-SH with greatest activity being obtained in the transfer of stearoyl and palmitoyl groups Rattus norvegicus CoA + L-acylcarnitine
-
 ?
acyl-CoA + L-carnitine CPT II requires preincubation with CoA-SH for manifestation of catalytic activity Rattus norvegicus CoA + L-acylcarnitine
-
 ?
acyl-CoA + L-carnitine isozyme CPT II catalyzes the reaction only in the direction towards long-chain fatty acyl-CoA formation, CPT I catalyzes reaction in both directions Rattus norvegicus CoA + L-acylcarnitine
-
 ?
palmitoyl-CoA + L-carnitine
-
 Rattus norvegicus CoA + L-palmitoylcarnitine
-
 ?
palmitoyl-CoA + L-carnitine
-
 Rattus norvegicus CoA + L-palmitoylcarnitine
-
 r