Any feedback?
Literature summary for 2.3.1.21 extracted from
- Carnitine palmitoyltransferases in pea leaf chloroplasts: partial purification, location, and properties (2000), Can. J. Bot., 78, 328-335.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| malonyl-CoA | inhibits CPT I not CPT II; regulatory role in vivo | Pisum sativum |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| chloroplast | inner envelope membrane with isoform CPT I on the outer, cytosolic side and isoform CPT II on the inner, stromal side of the membrane | Pisum sativum | 9507 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 20000 | - |
x * 20000, CPT I and II, SDS-PAGE | Pisum sativum |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acyl-CoA + L-carnitine | Pisum sativum | enzyme has a key function in regulation of fatty acid beta-oxidation | CoA + L-acylcarnitine | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pisum sativum | - |
2 isoforms CPTo (I) and CPTi (II) | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial, CPT I and II | Pisum sativum |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| leaf | CPT I and CPT II | Pisum sativum | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.0073 | - |
solubilized CPT | Pisum sativum |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acyl-CoA + L-carnitine | substrate specificity | Pisum sativum | CoA + L-acylcarnitine | - |
r | |
| acyl-CoA + L-carnitine | preference for desaturated long-chain acyl CoAs | Pisum sativum | CoA + L-acylcarnitine | - |
r | |
| acyl-CoA + L-carnitine | C4 to C18 acyl-CoAs | Pisum sativum | CoA + L-acylcarnitine | - |
r | |
| acyl-CoA + L-carnitine | enzyme has a key function in regulation of fatty acid beta-oxidation | Pisum sativum | CoA + L-acylcarnitine | - |
r | |
| linoleoyl-CoA + L-carnitine | preference for | Pisum sativum | CoA + L-linoleoylcarnitine | - |
r | |
| palmitoyl-CoA + DL-carnitine | - |
Pisum sativum | CoA + DL-palmitoylcarnitine | - |
r | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 20000, CPT I and II, SDS-PAGE | Pisum sativum |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 27 | - |
assay at | Pisum sativum |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
assay at | Pisum sativum |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
