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Literature summary for 2.3.1.21 extracted from
- Functional effects of protein kinases and peroxynitrite on cardiac carnitine palmitoyltransferase-1 in isolated mitochondria (2010), Mol. Cell. Biochem., 337, 223-237.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| malonyl-CoA | - |
Rattus norvegicus |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Rattus norvegicus | 5739 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| heart | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-carnitine + palmitoyl-CoA | - |
Rattus norvegicus | L-palmitoylcarnitine + CoA | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| carnitine palmitoyltransferase-1 | - |
Rattus norvegicus |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.0768 | - |
mitochondrial isolate | Rattus norvegicus | malonyl-CoA | |
| 0.1103 | - |
mitochondrial isolate, after incubation with protein kinase A | Rattus norvegicus | malonyl-CoA | |
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Release 2023.1 (January 2023)
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