Cloned (Comment) | Organism |
---|---|
gene pksA, DNA and amino acid sequence determination and analysis | Aspergillus parasiticus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of strain SRRC 2043, a disruption mutant defective in the pksA locus | Aspergillus parasiticus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus parasiticus | Q12053 | gene pksA | - |
Aspergillus parasiticus SRRC 2043 / RHN1 | Q12053 | gene pksA | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
mycelium | - |
Aspergillus parasiticus | - |
General Information | Comment | Organism |
---|---|---|
evolution | the pksA gene is located in the aflatoxin pathway gene cluster and is linked to the nor-1 gene, an aflatoxin pathway gene required for converting norsolorinic acid to averantin | Aspergillus parasiticus |
malfunction | strain SRRC 2043 is a disruption mutant defective in the pksA locus. Disruption of pksA results in an inability to produce aflatoxin intermediates | Aspergillus parasiticus |
metabolism | pksA is a polyketide synthase gene required for the early steps of aflatoxin biosynthesis | Aspergillus parasiticus |