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Literature summary for 2.3.1.23 extracted from

  • Richard, M.G.; McMaster, C.R.
    Lysophosphatidylcholine acyltransferase activity in Saccharomyces cerevisiae: regulation by a high-affinity Zn2+ binding site (1998), Lipids, 33, 1229-1234.
    View publication on PubMed
Search for more literature for 2.3.1.23

Activating Compound

Activating Compound Comment Organism Structure
cardiolipin 236% activation Saccharomyces cerevisiae
phosphatidic acid 182% activation Saccharomyces cerevisiae
phosphatidylinositol 212% activation Saccharomyces cerevisiae

Inhibitors

Inhibitors Comment Organism Structure
o-phenanthroline 2 mM, 82% inhibition, 1 mM, 73% inhibition Saccharomyces cerevisiae
Zn2+ 0.1 mM, 67% inhibition, 1 mM, 93% inhibition Saccharomyces cerevisiae

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.069
-
 1-acyl-sn-glycero-3-phosphocholine
-
 Saccharomyces cerevisiae
0.152
-
 oleoyl-CoA
-
 Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Saccharomyces cerevisiae CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
 r
acyl-CoA + 1-O-alkyl-sn-glycero-3-phosphocholine
-
 Saccharomyces cerevisiae CoA + 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?
acyl-CoA + 1-oleoyl-sn-glycero-3-phosphocholine preferred acyl acceptors in descending order: 1-oleoyl-sn-glycero-3-phosphocholine, 1-myristoyl-sn-glycero-3-phosphocholine, 1-lauroyl-sn-glycero-3-phosphocholine, 1-stearoyl-sn-glycero-3-phosphocholine, 1-palmitoyl-sn-glycero-3-phosphocholine, 1-decanoyl-sn-glycero-3-phosphocholine and 1-arachidonoyl-sn-glycero-3-phosphocholine Saccharomyces cerevisiae CoA + 1-oleoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?
oleoyl-CoA + lysophosphatidyl choline
-
 Saccharomyces cerevisiae ?
-
 ?