Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.1.23 extracted from

  • Chambers, K.; Brown, W.J.
    Characterization of a novel CI-976-sensitive lysophospholipid acyltransferase that is associated with the Golgi complex (2004), Biochem. Biophys. Res. Commun., 313, 681-686.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)-dodecanamide
-
Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
Golgi membrane associated with, catalytic domain of the enzyme is exposed to the cytosol rather than to lumen of the Golgi cisternae Rattus norvegicus 139
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Rattus norvegicus
-
heart
-
Rattus norvegicus
-
intestine very low activity Rattus norvegicus
-
kidney low activity Rattus norvegicus
-
liver
-
Rattus norvegicus
-
lung
-
Rattus norvegicus
-
muscle
-
Rattus norvegicus
-
pancreas very low activity Rattus norvegicus
-
spleen
-
Rattus norvegicus
-
testis
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
palmitoyl-CoA + lysophosphatidylcholine
-
Rattus norvegicus CoA + ?
-
?

Synonyms

Synonyms Comment Organism
LPAT
-
Rattus norvegicus
lysophospholipid acyltransferase
-
Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7 8 Golgi-associated enzyme Rattus norvegicus

pH Range

pH Minimum pH Maximum Comment Organism
6 10 pH 6.0: about 55% of maximal activity, pH 10.0: about 80% of maximal activity, Golgi-associated enzyme Rattus norvegicus