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Literature summary for 2.3.1.234 extracted from

  • Perrochia, L.; Crozat, E.; Hecker, A.; Zhang, W.; Bareille, J.; Collinet, B.; van Tilbeurgh, H.; Forterre, P.; Basta, T.
    In vitro biosynthesis of a universal t6A tRNA modification in Archaea and Eukarya (2013), Nucleic Acids Res., 41, 1953-1964.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
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Pyrococcus abyssi

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-threonylcarbamoyladenylate + adenine37 in tRNA Pyrococcus abyssi the enzyme is involved in the synthesis of N6-threonylcarbamoyladenosine37 in tRNAs, which is found in tRNAs with the anticodon NNU, i.e. tRNAIle, tRNAThr, tRNAAsn, tRNALys, tRNASer and tRNAArg AMP + N6-L-threonylcarbamoyladenine37 in tRNA
-
?
L-threonylcarbamoyladenylate + adenine37 in tRNA Pyrococcus abyssi GE5 / CNCM I-1302 / DSM 25543 the enzyme is involved in the synthesis of N6-threonylcarbamoyladenosine37 in tRNAs, which is found in tRNAs with the anticodon NNU, i.e. tRNAIle, tRNAThr, tRNAAsn, tRNALys, tRNASer and tRNAArg AMP + N6-L-threonylcarbamoyladenine37 in tRNA
-
?

Organism

Organism UniProt Comment Textmining
Pyrococcus abyssi Q9UXT7
-
-
Pyrococcus abyssi GE5 / CNCM I-1302 / DSM 25543 Q9UXT7
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-

Purification (Commentary)

Purification (Comment) Organism
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Pyrococcus abyssi

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-threonylcarbamoyladenylate + adenine37 in tRNA
-
Pyrococcus abyssi AMP + N6-L-threonylcarbamoyladenine37 in tRNA
-
?
L-threonylcarbamoyladenylate + adenine37 in tRNA the enzyme is involved in the synthesis of N6-threonylcarbamoyladenosine37 in tRNAs, which is found in tRNAs with the anticodon NNU, i.e. tRNAIle, tRNAThr, tRNAAsn, tRNALys, tRNASer and tRNAArg Pyrococcus abyssi AMP + N6-L-threonylcarbamoyladenine37 in tRNA
-
?
L-threonylcarbamoyladenylate + adenine37 in tRNA
-
Pyrococcus abyssi GE5 / CNCM I-1302 / DSM 25543 AMP + N6-L-threonylcarbamoyladenine37 in tRNA
-
?
L-threonylcarbamoyladenylate + adenine37 in tRNA the enzyme is involved in the synthesis of N6-threonylcarbamoyladenosine37 in tRNAs, which is found in tRNAs with the anticodon NNU, i.e. tRNAIle, tRNAThr, tRNAAsn, tRNALys, tRNASer and tRNAArg Pyrococcus abyssi GE5 / CNCM I-1302 / DSM 25543 AMP + N6-L-threonylcarbamoyladenine37 in tRNA
-
?

Subunits

Subunits Comment Organism
More Kae1 is part of a conserved protein complex named kinase, endopeptidase and other proteins of small size (KEOPS) Pyrococcus abyssi

Synonyms

Synonyms Comment Organism
Kae1 Kae1 is part of a conserved protein complex named kinase, endopeptidase and other proteins of small size (KEOPS) Pyrococcus abyssi
Qri7
-
Pyrococcus abyssi
t6A synthase
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Pyrococcus abyssi
ygjD
-
Pyrococcus abyssi

General Information

General Information Comment Organism
physiological function the enzyme is involved in the synthesis of N6-threonylcarbamoyladenosine37 in tRNAs, which is found in tRNAs with the anticodon NNU, i.e. tRNAIle, tRNAThr, tRNAAsn, tRNALys, tRNASer and tRNAArg Pyrococcus abyssi