Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
277000 | - |
- |
Aspergillus terreus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + malonyl-CoA + [2-methylbutanoate polyketide synthase] + 2 NADPH + 2 H+ + S-adenosyl-L-methionine | Aspergillus terreus | the enzyme is involved in the lovastatin biosynthetic pathway | (S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase] + 2 CoA + CO2 + 2 NADP+ + S-adenosyl-L-homocysteine + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus terreus | Q9Y7D5 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + malonyl-CoA + [2-methylbutanoate polyketide synthase] + 2 NADPH + 2 H+ + S-adenosyl-L-methionine | the enzyme is involved in the lovastatin biosynthetic pathway | Aspergillus terreus | (S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase] + 2 CoA + CO2 + 2 NADP+ + S-adenosyl-L-homocysteine + H2O | - |
? | |
acetyl-CoA + malonyl-CoA + [2-methylbutanoate polyketide synthase] + 2 NADPH + 2 H+ + S-adenosyl-L-methionine | the overall reaction comprises a single condensation reaction followed by alpha-methylation, beta-ketoreduction, dehydration, and alpha,beta enoyl reduction | Aspergillus terreus | (S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase] + 2 CoA + CO2 + 2 NADP+ + S-adenosyl-L-homocysteine + H2O | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | 277000, calculated from sequence | Aspergillus terreus |
Synonyms | Comment | Organism |
---|---|---|
LocF | - |
Aspergillus terreus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
4'-phosphopantetheine | covalently bound | Aspergillus terreus |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme is involved in the lovastatin biosynthetic pathway | Aspergillus terreus |