KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0022 | - |
elaidoyl-CoA | - |
Rattus norvegicus | |
0.0028 | - |
linoleoyl-CoA | - |
Rattus norvegicus | |
0.004 | - |
oleoyl-CoA | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required for the acylation of free cholesterol | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + cholesterol | acyl-CoA derivatives can be replaced by ATP, Mg2+, CoA and fatty acids, in-situ production of acyl-CoA | Rattus norvegicus | CoA + cholesterol ester | - |
? | |
acyl-CoA + cholesterol | the animal enzyme is highly specific for transfer of acyl groups with a single cis-double-bond 9 carbon atoms distant from the carboxyl group | Rattus norvegicus | CoA + cholesterol ester | - |
? | |
elaidoyl-CoA + cholesterol | - |
Rattus norvegicus | CoA + cholesteryl elaidate | - |
? | |
linelaidoyl-CoA + cholesterol | - |
Rattus norvegicus | CoA + cholesteryl linelaidate | - |
? | |
linoleoyl-CoA + cholesterol | - |
Rattus norvegicus | CoA + cholesteryl linoleate | - |
? | |
oleoyl-CoA + cholesterol | highest activity | Rattus norvegicus | CoA + cholesteryl oleate | - |
? | |
palmitoyl-CoA + cholesterol | - |
Rattus norvegicus | CoA + cholesteryl palmitate | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
CoA | required by the in-situ acyl-CoA production | Rattus norvegicus |