Literature summary for 2.3.1.26 extracted from

Song, B.L.; Wang, C.H.; Yao, X.M.; Yang, L.; Zhang, W.J.; Wang, Z.Z.; Zhao, X.N.; Yang, J.B.; Qi, W.; Yang, X.Y.; Inoue, K.; Lin, Z.X.; Zhang, H.Z.; Kodama, T.; Chang, C.C.; Liu, Y.K.; Chang, T.Y.; Li, B.L.
Human acyl-CoA:cholesterol acyltransferase 2 gene expression in intestinal Caco-2 cells and in hepatocellular carcinoma (2006), Biochem. J., 394, 617-626.

Search for more literature for 2.3.1.26

Application

Application	Comment	Organism
medicine	elevated ACAT2expression may serve as a new biomarker for certain forms of hepatocellular carcinoma	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	O75908	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
Hep-G2 cell	the CDX2 (caudal type homeobox transcription factor 2) expression is elevated, accounting for its elevated ACAT2 expression	Homo sapiens	-
hepatocellular carcinoma cell	high percentage (seven of fourteen) of liver samples from patients affected with hepatocellular carcinoma exhibit elevated ACAT2 expression	Homo sapiens	-
intestine	-	Homo sapiens	-
liver	in normal adult human liver, CDX2 (caudal type homeobox transcription factor 2) expression is not detectable and the ACAT2 expression is very low	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	ACAT2 plays an important role in intestinal cholesterol absorption	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
acyl-CoA:cholesterol acyltransferase 2	-	Homo sapiens

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Release 2023.1 (January 2023)