Cloned (Comment) | Organism |
---|---|
gene argJ, recombinant overexpression in Corynebacterium glutamicum strain ATCC 13032 | Corynebacterium glutamicum |
Protein Variants | Comment | Organism |
---|---|---|
additional information | L-citrulline overproduction in Corynebacterium glutamicum engineered strain correlates with expression levels of ArgJ, which plays a vital role in the L-citrulline biosynthesis | Corynebacterium glutamicum |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
L-citrulline | - |
Corynebacterium glutamicum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
N2-acetyl-L-ornithine + L-glutamate | Corynebacterium glutamicum | - |
L-ornithine + N-acetyl-L-glutamate | - |
? | |
N2-acetyl-L-ornithine + L-glutamate | Corynebacterium glutamicum ATCC 13032 | - |
L-ornithine + N-acetyl-L-glutamate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Corynebacterium glutamicum | Q59280 | gene argJ | - |
Corynebacterium glutamicum ATCC 13032 | Q59280 | gene argJ | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N2-acetyl-L-ornithine + L-glutamate | - |
Corynebacterium glutamicum | L-ornithine + N-acetyl-L-glutamate | - |
? | |
N2-acetyl-L-ornithine + L-glutamate | - |
Corynebacterium glutamicum ATCC 13032 | L-ornithine + N-acetyl-L-glutamate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
argJ | - |
Corynebacterium glutamicum |
OATase | - |
Corynebacterium glutamicum |
ornithine acetyltransferase | - |
Corynebacterium glutamicum |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Corynebacterium glutamicum |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Corynebacterium glutamicum |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
30 | - |
pH 7.5, 37°C | Corynebacterium glutamicum | L-citrulline |
General Information | Comment | Organism |
---|---|---|
metabolism | ArgJ plays a vital role in the L-citrulline biosynthesis. The enzyme exerts feedback inhibition on N-acetylglutamate synthase, pathway overview | Corynebacterium glutamicum |