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Literature summary for 2.3.1.43 extracted from

  • Jauhiainen, M.; Yuan, W.; Gelb, M.H.; Dolphin, P.J.
    Human plasma lecithin-cholesterol acyltransferase. Inhibition of the phospholipase A2-like activity by sn-2-difluoroketone phosphatidylcholine analogues (1989), J. Biol. Chem., 264, 1963-1967.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Sn-2-Difluoroketone phosphatidylcholine analogues IC50 values between 0.5 and 0.028 mM Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
plasma
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphatidylcholine + sterol cholesterol as substrate Homo sapiens 1-acylglycerophosphocholine + sterol ester
-
r

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.5 0.028 IC50 values between 0.5 and 0.028 mM Homo sapiens Sn-2-Difluoroketone phosphatidylcholine analogues