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Literature summary for 2.3.1.43 extracted from

  • Furukawa, Y.; Urano, T.; Itoh, H.; Takahashi, C.; Kimura, S.
    Isolation and properties of rat plasma lecithin-cholesterol acyltransferase (1989), J. Biochem., 105, 962-967.
    View publication on PubMed

General Stability

General Stability Organism
apo-A-1 prevents inactivation in phosphate buffer Rattus norvegicus
less stable than human enzyme to ionic strength Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
rat
-

Purification (Commentary)

Purification (Comment) Organism
precipitation from plasma with dextran sulfate-Ca2+ followed by DEAE-Sephadex A-50 and ion-exchange chromatography, rat enzyme is not absorbed on hydroxyapatite, which is employed for the purification of the human enzyme Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
plasma
-
Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.14
-
in cholesterol-lecithin vesicles activated with rat apolipoprotein A1 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphatidylcholine + sterol
-
Rattus norvegicus 1-acylglycerophosphocholine + sterol ester
-
r